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Young Bui, D.D.S.
MTA: An Excellent Concrete Material
Young Bui

Young Bui

MTA, mineral trioxide aggregate, is a new material developed for endodontics use.  MTA appears to be a significant improvement over other materials for procedures in bone.  Unlike ZOE cement, amalgam, and resin composite, which resulted in the formation of fibrous connective tissue adjacent to the bone, MTA allows osteoblasts to attach and spread on it with little or no tissue inflammation.  It is the first restorative material that consistently allows for the overgrowth of cementum.  Schwartz et al (July 1999) showed that root ends filled with MTA had a complete layer of cementum over the filling.  Comparing gap sizes between the root-end filling materials and their surrounding dentin shows that MTA had better adaptation compared with amalgam, Super-EBA, and IRM.  This improved adaptation allows MTA to provide a better seal when used as retrograde filling. 
    Keiser et al (May 2000) compare the cytotoxicity of MTA to other commonly used retrofilling materials, Super-EBA and amalgam.  In the freshly mixed state, the sequence of toxicity was amalgam > Super-EBA > MTA.  In the twenty-four-hour set state, the sequence of toxicity at a low extract concentration was Super-EBA > MTA, amalgam, and Super-EBA > amalgam > MTA at a higher extract concentration.  Torabinejad et al (July 1998) showed the tissue reaction to implanted MTA, amalgam, IRM, and Super-EBA in the tibias and mandibles of guinea pigs.  The tissue reaction to MTA implantation was the most favorable observed at both sites.  In the tibia, MTA was the material most often observed with direct bone apposition.
    There are many uses for MTA in addition to its use as a root-end filling.  MTA can be used to seal perforations; it acts as a pulp capping material; it produces apical hard tissue formation in immature teeth; and it acts as an apical barrier in open apex cases. 
    Sealing off the perforation site immediately during the initial visit will give the best prognosis for the tooth.  The trick for sealing mid-root strip perforation is to first clean out the canal completely and then fill it with gutta percha and sealer.  Next, remove the gutta percha to about 2 mm below the perforation and irrigate out the debris.  Next, mix the MTA to a putty consistency and pack it down the canal with either a plugger or a medium-size gutta percha.  The trick to mixing the MTA is not to have it too dry.  If it is too dry, it will fall apart on you as you try to pick it up.  Use enough water to make it into a putty so that you can pick it up easily. 
    MTA can be used as a pulp capping material in vital mechanical exposure or in primary tooth pulpotomy.  Ford et al (October 1996) found that pulps capped with MTA had no pulpal inflammation after five months in five of six samples and all six pulps in this group had a complete dentin bridge formation.  In contrast, all the pulps capped with Ca(OH)2 showed pulpal inflammation, and bridge formation occurred in only two samples.  Eidelman, Holan, and Fuks (January 2001) did a study to compare the effect of MTA with that of formocresol as pulp-dressing agents in pulpotomized primary molars with carious pulp exposure.  They found that none of the MTA-treated teeth showed any clinical or radiographic pathology at a 17-month recall. 
    Ca(OH)2 has been the material of choice for apexification in vital teeth.  Shabahang et al (January 1999) showed that MTA produced apical hard tissue formation with significantly greater consistency than Ca(OH)2 or osteogenic protein-1.  For non-vital open apex cases, MTA can be packed down to the apex and the canal can be filled in on the same visit.  The MTA will act as an apical barrier and allow for bone to grow around it.  The radiograph in Figure 1 shows the before and after of a non-vital open apex sealed with MTA and gutta percha in a one-visit treatment.
    I’m sure that you are probably saying, “Wow, great stuff!  But how much will it cost me?”  MTA is being sold in six one-gram packages for $249, manufactured by Tulsa Dentsply.  Holland (2001) compared the healing property of MTA and Portland cement as a pulp-capping material and found no difference between the two.  MTA has the same chemical properties as Portland cement except that MTA also has bismuth to give it a more opaque look in a radiograph.
January-February 2002
Figure 1

 FIGURE 1: Radiograph showing a non-vital open apex before sealing.
 
 

Figure 2

FIGURE 2: Radiograph showing a non-vital open apex after sealing with MTA and gutta percha in a one-visit treatment. 

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