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Young Bui, D.D.S.
Who Should Be Given Antibiotic Prophylaxis?
Young Bui

Young Bui

BEFORE TREATING patients, we should always take a good medical history.  Always go over the questions with the patients to make certain that they understand the technical terms.  Be sure to ask whether they have had a disease or medical problem that is not listed on the history form.  Investigate further about systemic diseases that they mark and ask what medications they are taking.  Certain patients will need to be pre-medicated before treatment to prevent systemic bacterial endocarditis (SBE).       Endocarditis occurs when bacteria enter the bloodstream and infect damaged endocardium or endothelial tissue located near high-flow shunts.  The dentist’s goal is to prevent endocarditis from occurring in susceptible dental patients.  Any dental procedure that causes injury to the soft tissue or bone, resulting in bleeding, can produce a transient bacteremia.  Below is a list of the frequency of bacteremia associated with various dental procedures and oral manipulations based on Bender in 1984 and Pallasch in 1989.
 
Periodontal surgery  88 %
Extractions 51-85 %
Periodontal scaling 8-80 %
Chewing 17-51 %
Dental prophylaxis 0-40 %
Toothbrushing 0-40 %
Endodontic therapy (non-vital) 0 %

     Consider antibiotic prophylaxis (AP) for dental work to minimize effects of bacteremia.  Besides the usual heart conditions that require AP, such as rheumatic fever, heart murmur, mitral valve prolapse with regurgitation, and congenital heart disease, many other conditions that require prophylaxis may be overlooked.  One example is HIV.  We seldom ask patients if they are HIV+ because we don’t want to embarrass patients or because we take universal precautions against HIV.  Not asking may be harmful to the patient.  A patient who contracted HIV from sharing needles is very likely to have had SBE previously, due to injecting bacteria directly into the bloodstream.  Infective endocarditis must be prevented in these patients.  AP is best avoided in AIDS patients unless severe neutropenia is present (<500 cells per mm3).  Under those conditions, the patient will require antibiotic prophylaxis. 
     Patients who had surgically corrected cardiovascular lesions should be given AP up to six months postoperatively.  Six months after surgery, most patients are no longer susceptible unless foreign material was used or if they have artificial heart valves. AP is required in patients with the latter two conditions.  In patients with pacemakers, a medical consultation is needed to determine whether AP is necessary.  It is not recommended by AHA, but some physicians may suggest it.  Patients on hemodialysis should be off the dialysis machine for at least four hours before a dental procedure because of heparin, and AP should be considered.  In patients with joint prosthesis, AP is not necessary unless they are in the “high risk” category, such as those with rheumatoid arthritis, diabetes, immuno-suppressed conditions, or previous infection. 
     The following bleeding disorders may cause the patient to have post-operative infection and therefore AP should be considered in surgical cases: thrombocytopenia, systemic lupus erythematosus, vascular wall alterations, hemophilia, von Willebrand’s disease, liver disease, and leukemia.

July-August 2001

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