Endo-Mail
 



Barry L. Musikant, D.M.D., F.A.C.D.
Knowing the Research Makes All the Difference
Barry Musikant

Barry Musikant

RECENTLY, a local endodontist distributed a newsletter quoting research from an article by Pommel et al stating that obturation with a single gutta-percha point produces the greatest amount of leakage.  From their conclusions he extrapolated the further conclusion that the EZ-Fill® Obturation System (Essential Dental Systems, Inc. S. Hackensack, NJ) would perform badly because it too is a single-point obturation system. The quoted authors conducted their research using a zinc-oxide-eugenol cement as the interface.  They noted that zinc oxide, unlike the epoxy resin used in EZ-Fill, hydrolizes in water.  The authors conjectured that zinc oxide would be prone to cement washout over time because the setting reaction is reversible in the presence of water, resulting in a degradation of the material and leaching of hydrolized eugenol and unreacted zinc oxide.  They concluded that the large volume of sealer used for the single-cone technique is more prone to shrinkage than the small volume used for compaction techniques.  However, epoxy resin’s setting reaction is not reversible in the presence of water, and because it is a polymer it is far tougher than the particulate zinc-eugenol cement.  The endodontist would not have come to the erroneous conclusion he reached if he had been aware of the differences in cement interfaces between zinc oxide eugenol and epoxy resins.
    Furthermore, several studies comparing single-cone techniques using epoxy-resin cements have attained different results. Wu, Ozok and Wesselink compared the sealer-coated canal perimeter at 3 mm and 6 mm from the apex and found significantly better seals after the single-cone obturation (with no condensation) than after vertical or lateral condensation. Antonopoulous, comparing lateral condensation with lateral condensation, found similar sealing abilities. Spangberg tested single-cone, lateral-condensation, vertical-condensation Thermafil and Ultrafil and found them all statistically the same, with the single-cone technique having the least deviation in results.  In a study published this year, Hata et al compared the apical sealing ability of System B, lateral condensation, and the EZ-Fill obturation technique, using a one-way analysis of variance, and found no significant difference among the groups.  However, the authors stated that the root canals obturated with the EZ-Fill technique showed the least dye penetration. Baumann et al compared the leakage of five different single-cone techniques with lateral condensation and concluded that some single-cone techniques with thermoplastic gutta percha and sealer or cold gutta percha and a new sealer application tool (EZ-Fill) can be an alternative to lateral and vertical condensation. Cohen et al compared the leakage of single-point fills using epoxy resins to lateral condensation and Thermafil and found them all statistically equal, with the single-point fill having the least leakage in absolute terms.
    In a study that addresses the long-term sealing ability of an epoxy-resin cement interface, Kontakotis, Wu, and Wesselink compared the performance of five sealers before and after storage in water for two years.  They concluded that Roth and Pulp Canal Sealer, both zinc-oxide-eugenol cements, allowed more leakage in thick layers than thin, whereas no significant difference was found between the thin and thick layers for the epoxy-resin cement. Cohen et al confirmed the weakness of zinc-oxide-eugenol cements compared with epoxy-resin cements.  The shear bond strength of the zinc-oxide-based cement was literally zero, while that of the EZ-Fill epoxy-resin was 323.9 psi.  No more-adhesive endodontic cement exists.
    Furthermore, Cohen determined that the free eugenol found in all zinc-oxide cements prevents the polymerization of composites and their bonding agents by scavenging the free radicals that initiate the polymerization process10. From a clinical point of view, using the EZ-Fill Obturation System, Deutsch et al reported a success rate of 94.1 percent over two-and-a-half years.
    A body of research has determined that the use of an epoxy-resin cement as an interface of varying thicknesses over at least two years is at least as effective as every other method of obturation.  From a mechanical point of view, one may believe that a single-point fill cannot obturate accessory canals.  Yet, obturating with EZ-Fill often shows lateral canals filled.  Unlike thermoplastic obturation, in which the canals are filled with gutta percha, the EZ-Fill technique predictably fills these canals with epoxy-resin cement.  The filling of these canals is clearly observed because the epoxy-resin cement is radiopaque.  The canals have been debrided both mechanically and chemically with NaOCl and are sufficiently open to allow the extrusion of material into these spaces.
    There is no innate superiority of gutta percha over epoxy-resin.  In fact, Lee has demonstrated that thermoplastic gutta percha contracts as it cools from a minimum of 45 minutes to 10 hours, shrinking approximately 4 percent in the process.  Epoxy-resin, on the other hand, goes into the canal at room temperature and expands approximately 1.75 percent as it warms from room to body temperature.  Not only does shrinkage continue far longer than the 10 seconds popularly believed, but very little cement can even be used during thermoplastic obturation.  Because the coronal escape route is closed off when obturating thermoplastically, any excess cement in the canal would be forced over the apex under significant pressure.  The single-point technique allows the safe coronal extrusion of excess cement and, consequently, cement can be used liberally both in the canal and on the point itself. Hall demonstrated that at best 62.5 percent of curved canal spaces are coated with cement with the traditional applicators, obviously less when thermoplastic techniques are used.  Therefore, combining a thermoplastic technique with an inadequate cement interface produces a result far removed from the three-dimensional claims made for it.
    To understand the EZ-Fill obturation system, you must appreciate the mechanics behind the bi-directional spiral.  The coronal spirals drive the cement apically while the three apical spirals drive the cement coronally.  These two cement flows collide and are driven laterally.  The spiral is used with an up-and-down hand motion, driving the cement against the canal walls and any accessory canals that may reside there, along its entire length.  The cement is driven further laterally when the coated tapered gutta-percha point is placed into the canal.  The EZ-Fill SafeSider instrumentation system rapidly shapes the canal to a minimum of an .08 mm/mm taper, which corresponds to a medium gutta-percha point.  The greater the taper of the gutta percha, the more the cement interface is driven laterally, which is why so many lateral canals are filled with this instrumentation and obturation system.
    Some other points to be considered: Floren et al noted that System B represented a narrow window of success because it is possible to cause thermal damage to the ligament if the temperature rise exceeds 10 degrees C, something that is more likely in canals with thin roots. Saw et al demonstrated that thermoplastic techniques not only caused a temperature rise in the tooth and ligament, but that this rise created dentinal stress and could lead to premature fracture. Jurcak et al reported that Touch N Heat produced increases in temperature from 8 to 67 degrees C and that this was a concern. E. M. Hardie reported on similar concerns for the same reasons.
    To further appreciate the utility of the EZ-Fill system, consider the following research: Zidan et al state that it appears that leakage is independent of the method of obturation when an adhesive sealer is used.  This can be attributed to the ability of the adhesive sealer to wet the walls of the canal, bond to the dentin, and seal the residual volume between gutta percha and the canal wall.  In fact, the literature shows that an epoxy-resin has strong adhesion to dentin and the gutta-percha point without the need of a dentinal bonding agent.  Opening the dentinal tubules of the canal with EDTA significantly increases the bond strength of the epoxy-resin cement to the dentinal walls. Gettleman et al compared the adhesion of three cements—AH-26, Sultan, and Sealapex—to dentin with the smear layer intact and the smear layer removed.  AH-26 has the highest adhesion to dentin when the smear layer is removed.
Limkangwalmongkol et al compared the sealing abilities of four root-canal cements, including Apexit, Sealapex, Tubli-Seal and AH-26.  AH-26 demonstrated a significantly better apical seal than the other sealers.  The authors note that from the findings of other studies AH-26 appears to have many advantages over other sealers.  It mixes easily, flows well, has ample working time, good radiopacity, comparable solubility, good adhesion and good biocompatibility.  It has also been shown to adhere to dentin that has been maintained in a moist state.  Of the materials tested in this study, AH-26 had the best working characteristics. Wu et al, in comparing the leakage of four sealers stored in water for one year, determined that AH26, Ketac-Endo, and Tubli-Seal showed a reduction in leakage over time and gave significantly less leakage than Sealapex. The authors also noted that AH26 gave a long-lasting seal when used as the sole material, showing its possible multiple applications.
    Those dentists who try the EZ-Fill Instrumentation and Obturation Systems will quickly find that they have the ability to produce the highest quality results more easily, quickly, simply, and far less expensively.  I hope that this detailed response to wayward conclusions sets things straight.  The research and our seven years of clinical results speak for themselves.  In the past you may have felt that you had to invest in complex, complicated, and expensive endodontic systems, but you can bring about a major reduction in your level of stress and financial costs if you adopt the EZ-Fill SafeSider Instrumentation and Obturation systems.

References

  1. Pommel L, Camps J. In Vitro Apical Leakage of System B Compared with Other Filling Techniques. J Endodon 2001;27:449-51.  [BACK]
  2. Wu M-K, Ozok R, Wesselink P R. Sealer distribution in root canals obturated by three techniques. International Endodontic J 2000;33:340-345.  [BACK]
  3. Antonopoulos K G, Attin T and Helwig E. Evaluation of the apical seal of root canal fillings with different methods. J Endodon 1998;24;655  [BACK]
  4. Dalat D M, Spangberg LSW. Comparison of apical leakage in root canals obturated with various gutta-percha techniques using a dye vacuum tracing method. J Endodon 1994; 20:315-9.  [BACK]
  5. Hata G, Imura N, Matsuda T, Kato A, Souza F J, Toda T. Apical sealing ability of the EZ-Fill obturation technique. J Endodon 2002; 28:260.  [BACK]
  6. Baumann M A, Loy R, Behrens O. Dye penetration of five different single cone techniques compared to lateral condensation. Abstract IADR/AADR/CADR 80th General Session March 2002  [BACK]
  7. Cohen B I, Pagnillo MK, Musikant B L and Deutsch A S. The evaluation of apical leakage for three endodontic fill systems. Gen Dent.1998; Nov-Dec: 618-23.  [BACK]
  8. Kontakiotis E G, Wu M-K, Wesselink P R. Effect of sealer thickness on long surface of the tooth during the thermo-mechanical compaction technique of root canal obturation. International Endodontic J. 1986; 19:73-77.  [BACK]
  9. Cohen B, Volovich S, Musikant B and Deutsch A. Shear bond strength for four endodontic sealers. Endodontic Practice; 3:9-14.  [BACK]
  10. Cohen BI, Volovich Y, Musikant B L and Deutsch A S. The Effects of Eugenol and Epoxy-Resin on the Strength of a Hybrid Composite Resin. J Endodon; 2:79-82.  [BACK]
  11. Deutsch A S, Cohen B I, Musikant B L, Kase D. A study of one-visit treatment using EZ-Fill root canal sealer. Endodontic Practice 2001 4:29-36.  [BACK]
  12. Lee C Q, Chang Y, Cobb C M, Robinson S, Hellmuth E M. Dimensional Stability of Thermosensitive Gutta-Percha. J Endodon; 23:579-582.  [BACK]
  13. Hall M C, Clement D J, Dove S B, Walker lll W A. A Comparison of Sealer Placement Techniques in Curved Canals. J Endodon 1996; 22: 638-642.  [BACK]
  14. Floren J W, Weller R N, Pashley D H, Kimbrough W F. Changes in Root Surface Temperatures with In Vitro Use of the System B HeatSource. J Endodon 1999; 25:593-595.  [BACK]
  15. Saw L-P, Messer H H. Root Strains Associated with Different Obturation Techniques. J Endodon 1995; 21:314-320.  [BACK]
  16. Jurcak J J, Weller R N, Kulild J C, Donley D L. In Vitro Intracanal Temperatures Produced during Warm Lateral Condensation of Gutta-percha. J Endodon 1992; 18:1-3.  [BACK]
  17. Hardie E M. Heat transmission to the outer surface of the tooth during the thermo-mechanical compaction technique of root canal obturation. International Endodontic J. 1986; 19:73-77.  [BACK]
  18. Zidan O, Al-Khatib Z, Gomez-Marin O. Obturation of root canals using the single cone gutta-percha technique and dentinal bonding agents. Internatinal Endodontic J 1987; 20:128-132.  [BACK]
  19. Gettleman B H, Messer H H, ElDeeb M E. Adhesion of Sealer Cements to Dentin with and without the Smear Layer. J Endodon 1991; 17:15-20.  [BACK]
  20. Limkangwalmongkol S, Burtscher P,  Abbott P V, Sandler A B, Bishop B M. A Comparative Study of the Apical Leakage of Four Root Canal Sealers and Laterally Condensed Gutta-percha. J Endodon 1991; 17:495-499.  [BACK]
  21. Wu M-K, Wesselink P R, Boersma J. A 1-year follow-up study on leakage of four root canal sealers at different thicknesses. International Endodontic J 1995; 28:185-189.  [BACK]
 

September-October 2002
A body of research has determined that the use of an epoxy-resin cement . . . is at least as effective as every other method of obturation.







FEEDBACK?
We welcome your responses and questions. 
Please feel free to visit the Endo Forum and add your comments about any of the articles in Endo-Mail.
© Copyright 2008 by Musikant, Deutsch, Kase, Dukoff, Bui, Lipner & Kim. All rights reserved.