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Amy Beth Dukoff, D.M.D.
Vicoprofen: Effective Pain Relief?
A Product Review
Amy Dukoff

Amy Dukoff

Vicoprofen combines two widely used analgesics.  It produces a wonderful combination for the management of dental pain.  The additive effect provides the doctor with an alternative for the patient seeking pain relief.
    The Vicoprofen tablet is 7.5 mg of Hydrocodone Bitrate with 200 mg of Ibuprofen. Hydrocodone Bitrate is a semi-synthetic, central acting opoid.  Ibuprofren is a non-steroidal anti-inflammatory, peripheral acting drug.  It is supplied in a fixed combination orally for short term usage (usually less than 10 days).  Any contraindications and warnings for Ibuprofren are the same for Hydrocodone and Ibuprofen respectively.
    Knoll Pharmaceutical Company provides research describing the analgesic.  They claim that there is a rapid onset of 11.0 to 16.2 minutes with its maximum effect in one hour.  They also claim that most adverse reactions were mild and moderate with gastrointestinal reactions common.  The manufacturer recommends 1 tablet every four to six hours with a maximum dosage of 5 tablets for a 24-hour period.  Their study found that one Vicoprofen (7.5 mg) was equal in relieving pain to two tablets of acetaminophen with codeine (300 mg/30 mg x 2).
    The suggested prescription is Vicoprofen #40 Tabs.  I usually dispense #12—#16, with instructions to take one tablet every 4-6 hours as needed for pain.
    I give this product a Four Star rating. I like hydrocodone for some of my patients because they tolerate it better than codeine.
    Some patients don’t like the side effects of codeine but aren’t allergic to it and would like pain relief similar to codeine’s narcotic effects. 
    Ibuprofen has also been shown to be effective in treating inflammation.  In the past, I have had the patients alternate between Tylenol with codeine and Advil. Vicoprofen in this combination seems to be effective and worth trying. 
11/02/1999

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